Continuous Time Survival in Latent Variable Models

Applications Of Continuous-Time Survival In Latent Variable Models For The Analysis Of Oncology Randomized Clinical Trial Data Using Mplus

Stratification of patient trajectories using covariate latent variable models

Standard models assign disease progression to discrete categories or stages based on wellcharacterized clinical markers. However, such a system is potentially at odds with our understanding of the underlying biology, which in highly complex systems may support a (near-)continuous evolution of disease from inception to terminal state. To learn such a continuous disease score one could infer a la...

Bayesian Sample Size Determination for Joint Modeling of Longitudinal Measurements and Survival Data

A longitudinal study refers to collection of a response variable and possibly some explanatory variables at multiple follow-up times. In many clinical studies with longitudinal measurements, the response variable, for each patient is collected as long as an event of interest, which considered as clinical end point, occurs. Joint modeling of continuous longitudinal measurements and survival time...

Distinguishing Between Latent Classes and Continuous Factors: Resolution by Maximum Likelihood?

Latent variable models exist with continuous, categorical, or both types of latent variables. The role of latent variables is to account for systematic patterns in the observed responses. This article has two goals: (a) to establish whether, based on observed responses, it can be decided that an underlying latent variable is continuous or categorical, and (b) to quantify the effect of sample si...

Using multivariate generalized linear latent variable models to measure the difference in event count for stranded marine animals

BACKGROUND AND OBJECTIVES: The classification of marine animals as protected species makes data and information on them to be very important. Therefore, this led to the need to retrieve and understand the data on the event counts for stranded marine animals based on location emergence, number of individuals, behavior, and threats to their presence. Whales are g...